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This is a vital moment in the life of The New York Times. Journalists across the organization are hungry to make change a reality, and we have new leaders ready to push us forward. While the past two years have been a time of significant innovation, the pace must accelerate. Too often, digital progress has been accomplished through workarounds; now we must tear apart the barriers. The New York Times has staked its future on being a destination for readers — an authoritative, clarifying and vital destination. These qualities have long prompted people to subscribe to our expertly curated print newspaper.
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The efficient knock-in of large DNA fragments to label endogenous proteins remains especially challenging in non-dividing cells such as neurons. To learn about protein function in complex systems biologists need tools to visualize endogenous proteins. A powerful approach to achieve this is the introduction of genetic tags to proteins of interest, fluorescent or otherwise. Endogenous protein labeling is highly advantageous compared to other approaches. First, it removes the dependence on specific antibodies which require extensive validation.
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The Scythians are frequently presented, in popular and academic thought alike, as highly mobile warrior nomads who posed a great economic risk to growing Mediterranean empires from the Iron Age into the Classical period. Archaeological studies provide evidence of first millennium BCE urbanism in the steppe while historical texts reference steppe agriculture, challenging traditional characterizations of Scythians as nomads. However, there have been few direct studies of the diet and mobility of populations living in the Pontic steppe and forest-steppe during the Scythian era.
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Content is everywhere. From books to magazines to essays and ads, the written word is used to convey a ton of information every day. Think about this:. As of January , there were million active websites, all of which are filled with content.
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